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Synthetic Biomaterials Mimic Cellular Membranes: Use in Nanomedicine, Drug Delivery

合成生物材料模拟细胞膜:用于纳米医学药物输送

ScienceDaily (May 23, 2010) — An international collaboration led by chemists and engineers from the University of Pennsylvania has prepared a library of synthetic biomaterials that mimic cellular membranes and that show promise in targeted delivery of cancer drugs, gene therapy, proteins, imaging and diagnostic agents and cosmetics safely to the body in the emerging field called nanomedicine.

每日科学(2010年5月23日) - 一个由美国宾州大学的化学家和工程师领导的国际合作小组制备了许多合成生物材料,这些生物材料能模拟细胞膜,且在新兴的纳米医学领域有目的得向人体安全输送抗癌药物,基因疗法,蛋白质,成像诊断试剂,化妆品等方面很有前景。

The study appears in the current issue of the journal Science.

这项研究发表在最近一期的科学杂志上。

The research provides the first description of the preparation, structure, self-assembly and mechanical properties of vesicles and other selected complex nano-assemblies made from Janus dendrimers.

该研究对这些囊泡和其他由贾纳斯人造分子组成的复杂纳米聚合物的制备、结构、自组装性及其医学性能做了首要说明。

The so-called dendrimersomes are stable, bilayer vesicles that spontaneously form from the exact chemical composition of Janus dendrimers.

这些所谓的人造分子成分是稳定的双分子囊泡,它们自动地由贾纳斯人造分子的精确化学成分转化形成。

The team reported a myriad of bilayer capsule populations, uniform in size, stable in time in a large variety of media and temperatures, that are tunable by temperature and chemistry with superior mechanical properties to regular liposomes and impermeable to encapsulated compounds.

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