食品安全学摘要翻译

Author： Malik, Ashok Kumar; Blasco, Cristina; Pico, Yolanda

Source：Journal of chromatography. A. 2010 June 18. 1217(25) p. 4018-4040.

Subject Headings：food contamination. chemical residues. liquid chromatography. mass

spectrometry. food safety. food analysis. drug residues. antibiotic residues.

toxins. pesticide residues. literature reviews.

Liquid chromatography-mass spectrometry in food safety

The use of powerful mass spectrometric detectors in combination with liquid chromatography has played a vital role to solve many problems related to food safety. but not restricted to the analysis of food contaminants within the food safety area, this review is focused on providing an insight into this field. The basic legislation in different parts of the world is discussed with a focus on the situation within the European Union (EU) and why it favors the use of liquid chromatography-mass spectrometry (LC-MS).Main attention in this review is on the achievements that have been possible because of the latest advances and novelties in mass spectrometry and how these progresses have influenced the best control of food allowing an increase in the food safety and quality standards. Emphasis is given to the potential and pitfalls of the different LC-MS approaches as well as in its possibilities to address current hot issues in food safety, such as the development of large-scale multi-residue methods and the identification of non-target and unknown compounds.Last but not least, future perspectives and potential directions are also outlined highlighting prospects and achievements.

译文：

液相色谱 - 质谱联用技术在食品安全中的应用

高效液相色谱结合质量光谱探测器联合使用，在解决食品安全有关的问题中起到了至关重要的作用。本文重点研究的是液相色谱-质谱联用技术在食品安全领域内对食品污染物进行高效、精确分析提供的技术保障，实际上因为这项技术具有极其广泛的适应性，所以不仅限于此。包括欧洲联盟（欧盟）在内的世界不同地区的基本法律都在关注着利用液相色谱-质谱联用技术的实际应用(LC-MS)。本文主要关注的是在质谱分析方面最新的进展和取得的成就，因为这些进展均是关于在不断变化的食品安全与质量标准的前提下如何控制影响食物的因素。需要强调的是不同的LC-MS方法以及它解决当前热点问题时暴露出的潜在能力与陷阱，例如大型的多残留分析方法的开发和非目标物或未知化合物的鉴别。最后前景展望和潜力的方向部分还概述了突出的前景和成就。